Researchers from the Yong Loo Lin School of Medicine at the National University of Singapore have identified the transcription factor DMTF1 as a protein that can enhance neural stem cell function in experimental ageing models.

• Technical Insight: The study found that restoring DMTF1 expression in human-derived cells and laboratory models improved the regeneration capacity of neural stem cells, and involved helper genes such as Arid2 and Ss18.
• Research Basis: Findings were published in Science Advances and derived from controlled experiments designed to simulate aspects of neural ageing.

This summary is based on a press release issued by NUS Medicine.